This book presents the select peer-reviewed proceedings of the Control Instrumentation and System Conference (CISCON 2022) held at Manipal Institute of Technology, MAHE, Manipal. It examines a wide spectrum covering the latest trends in the fields of instrumentation, sensors and systems, and industrial automation and control. The topics covered include image and signal processing, robotics, renewable energy, power systems, and power drives, performance attributes of MEMS, multi-sensor data fusion, machine learning, optimization techniques, process control, safety monitoring, safety-critical control, supervisory control, system modeling and virtual instrumentation. The book is a valuable reference for researchers and professionals interested in sensors, adaptive control, automation and control, and allied fields.