This book constitutes the refereed proceedings of the 10th Annual International Conference on Information Management and Big Data, SIMBig 2023, held in Mexico City, Mexico, during December 13-15, 2023. The 19 full papers and 6 short papers included in this book were carefully reviewed and selected from 64 submissions. SIMBig 2023 introduced innovative approaches for analyzing and handling datasets as well as new methods based on Artificial Intelligence (AI), Data Science, Machine Learning, Natural Language Processing, Semantic Web, Data-driven Software Engineering, Health Informatics, and more.