This book constitutes the refereed proceedings of the 12th Ecuadorian Conference on Information and Communication Technologies, TICEC 2024, held in Loja, Ecuador, during October 16-18, 2024. The 24 full papers presented here were carefully reviewed and selected from 74 submissions. They were organized in the following topical sections: Image Processing, Classification, and Segmentation; Artificial Intelligence and Machine Learning Applications; IoT, Embedded Systems, and Applications in Healthcare and Industrial Environments.