The two-volume set LNCS 15404 and 15405 constitutes the refereed proceedings of the 22nd International Conference on Service-Oriented Computing, ICSOC 2024, held in Tunis, Tunisia, during December 3-6, 2024. The 38 full papers and 19 short papers presented in these proceedings were carefully reviewed and selected from 255 submissions. The papers are organized in the following topical sections: Part I: Edge and IoT; Generative AI; Service Security and Privacy; and Processes and Workflows. Part II: Cloud Computing; QoS and SLA; Microservice; Service Recommendation; Emerging Technologies and Approaches; Service Composition; Blockchain; and Industry Papers.