This two-volume set CCIS 2208-2209 constitutes revised selected papers from the refereed proceedings of the 18th Colombian Congress on Computing, CCC 2024, held in Manizales, Colombia, during September 4-6, 2024. The 50 full papers and 5 short papers included in this book were carefully reviewed and selected from 124 submissions. They were organized in topical sections as follows: Artificial Intelligence; Pattern recognition and computer vision; Computational statistics and formal methods; Cyber security and information security; Data, information and knowledge; ICT for education and e-Learning; Industry 4.0 and digital transformation; Software engineering and automation.