This two-volume set constitutes the revised selected papers of the 6th International Conference on Advanced Informatics for Computing Research, ICAICR 2023 held in Rohtak, Haryana, India, in December 16-17, 2023. The 58 full papers presented in these proceedings were carefully reviewed and selected from 225 submissions. They are organized in topical sections as follows: Volume number 2072: Artificial Intelligence; Data Science; Human computer interaction (HCI), Machine Learning. Volume number 2073: Machine Learning; Security and Privacy.