This book presents a set of innovative solutions to human-centric manufacturing systems, offering critical insights and comprehensive application guidelines for understanding how to realize human-centric smart manufacturing by exerting its power and influence towards Industry 5.0. While human-centric manufacturing possesses a substantial and growing body of knowledge, there are distinct research gaps that are not sufficiently addressed. With the development of enabling technologies, it is necessary to propose more precise, robust, and practical approaches in support of smart manufacturing towards Industry 5.0. As a response to the new research opportunities, this book presents and highlights the latest development on applying advanced techniques in human-centric manufacturing. The book will be of interest to a broad readership, from academic researchers to practicing engineers.