This book constitutes the proceedings of the 25th International Conference on Business Information Systems, BIS 2025, which took place in Poznan, Poland, during June 25-27, 2025. This year's theme was "AI-driven business transformation: challenges and opportunities". The 19 full papers and 4 short papers presented in this volume were carefully reviewed and selected from 54 submissions. The papers were organized in the following topical sections: Artificial intelligence in management; artificial intelligence for visualization; artificial intelligence for language processing; process mining; finance and privacy; data platforms and deployment; sustainable operations and smart automation.