This book provides a comprehensive overview of circular RNAs (circRNAs), a novel class of non-coding RNAs with diverse regulatory roles and clinical relevance. Covering recent advances in circRNA biogenesis, molecular mechanisms, computational tools, and disease associations, it offers a structured and up-to-date resource. Readers will gain insights into how circRNAs influence gene regulation, participate in human diseases, and serve as potential biomarkers and therapeutic targets. This book is ideal for researchers, clinicians, and students interested in RNA biology, bioinformatics, and precision medicine.