This book constitutes the proceedings of the 18th International Conference on Coordination Models and Languages, COORDINATION 2016, held in Heraklion, Crete, Greece, in June 2016, as part of the 11th International Federated Conference on Distributed Computing Techniques, DisCoTec 2016. The 16 full papers included in this volume were carefully reviewed and selected from 44 submissions. The papers cover a wide range of topics and techniques related to system coordination, including: programming and communication abstractions; communication protocols and behavioural types; actors and concurrent objects; tuple spaces; games, interfaces and contracts; information flow policies and dissemination techniques; and probabilistic models and formal verification.