This book constitutes the refereed proceedings of the 10th International Conference on Security, Privacy and Anonymity in Computation, Communication, and Storage, SpaCCS 2017, held in Guangzhou, China, in December 2017. The 47 papers presented in this volume were carefully reviewed and selected from 140 submissions. They deal with research findings, achievements, innovations and perspectives in information security and related fields covering topics such as security algorithms and architectures, privacy-aware policies, regulations and techniques, anonymous computation and communication, encompassing fundamental theoretical approaches, practical experimental projects, and commercial application systems for computation, communication and storage.