This book constitutes the refereed proceedings of the 13th International Conference on Information Systems Security, ICISS 2017, held in Mumbai, India, in December 2017. The 17 revised full papers and 7 short papers presented together with 2 invited papers were carefully reviewed and selected from 73 submissions. The papers address the following topics:  privacy/cryptography, systems security, security analysis, identity management and access control, security attacks and detection, network security.