This book constitutes the refereed proceedings of the 17th IFIP WG 8.1 International Conference on Informatics and Semiotics in Organisations, ICISO 2016, held in Campinas, Brazil, in August 2016. The 16 full papers and 9 short papers presented were carefully reviewed and selected from 30 submissions. The papers are organized in the following topical sections: organisational semiotics: theory and research; semiotics of interactions and socially aware user interface design; digital business ecosystems; knowledge management and engineering; and trends, challenges and new issues in education, health and eScience systems.