This book constitutes the refereed proceedings of the 7th International Conference of the CLEF Initiative, CLEF 2016, held in Toulouse, France, in September 2016. The 10 full papers and 8 short papers presented together with 5 best of the labs papers were carefully reviewed and selected from 36 submissions. In addition to these talks, this volume contains the results of 7 benchmarking labs reporting their year long activities in overview talks and lab sessions. The papers address all aspects of information access in any modality and language and cover a broad range of topics in the fields of multilingual and multimodal information access evaluation.