Title:
Statistical and computational pharmacogenomics
Author:
Wu, Rongling.
ISBN:
9781584888291
Publication Information:
Boca Raton : Chapman & Hall/CRC, 2008.
Physical Description:
368 p.
Series:
Chapman & Hall/CRC interdisciplinary statistics series
Series Title:
Chapman & Hall/CRC interdisciplinary statistics series
Contents:
Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics link model -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response.
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