Part I: Diagnosis of Osteomyelitis -- Clinical and laboratory diagnosis of osteomyelitis -- Diagnostic imaging for osteomyelitis -- Bone biopsy techniques -- Microbiology of osteomyelitis -- Pathologic diagnosis of osteomyelitis -- Part II: Medical Treatment Guidelines for Osteomyelitis -- Part III: Surgical Treatment Principles for Diabetic Ulcer Related Osteomyelitis -- Surgical treatment principles for diabetic wounds complicated by osteomyelitis -- Antibiotic bead Protocol -- Prevention of heterotopic ossification in diabetic foot surgery -- Infected Charcot arthropathy -- Part IV: Surgical Procedures for Osteomyelitis Based on Diabetic Ulcer Location -- Tip of hallux ulcer with distal phalanx osteomyelitis (hallux distal Symes amputation) -- Hallux plantar IPJ ulcer with osteomyelitis (IPJ arthroplasty with uni-lobed flap) -- 1st MPJ ulcer with localized sesamoid osteomyelitis (O to Z flap with sesamoidectomy) -- 1st and 5th MPJ plantar ulcer with osteomyelitis (1st and 5th ray amp flap) -- Complete 5th ray amputation for recurrent osteomyelitis of the shaft or base -- Tip of lesser toe ulcer with osteomyelitis (office based distal Symes) -- Central ray ulcer with metatarsal or phalanx osteomyelitis -- Midfoot ulcer with tarsal bone osteomyelitis (Chopart's considerations) -- Decubitus heel ulcer with calcaneal osteomyelitis (partial calcanectomy with uni-lobed flap) -- Lateral ankle decubitus ulcer with distal fibula osteomyelitis (partial fibulectomy with advancement flap) -- Part V: Trauma-Related Osteomyelitis (puncture wound, GSW and open fracture) -- Part VI: Hematogenous Bone and Joint Infection -- Hematogenous osteomyelitis -- Septic ankle joint -- Part VII: Post-operative Osteomyelitis -- Management of infected nonunion and infected hardware -- Osteomyelitis associated with external fixation.