Part I Epidemiology -- 1 Prevalence and Transmission Routes of H. pylori -- Part II Pathophysiology -- 2 Gastric Colonization by H. pylori -- 3 Immunological Reactions on H. pylori Infection -- 4 Change of Acid Secretions, Ghrelin and Leptin, by H. pylori -- 5 H. pylori Virulence Factors: Toxins (CagA, VacA, DupA, OipA, IceA) -- 6 H. pylori Virulence Factors: Genetic Polymorphism and Disease -- 7 Host Factor: Genetic Polymorphism -- Part III Diagnosis -- 8 Serology -- 9 Histopathologic Diagnosis of H. pylori Infection and Associated Gastric Diseases -- 10 Culture -- 11 Urea Breath Test -- 12 H. pylori Stool Antigen Test -- 13 Specific Conditions: Children -- 14 Specific Conditions: Diagnosis of H. pylori Infection in Case of Upper Gastrointestinal Bleeding -- Part IV Symptom -- 15 Symptoms of Acute and Chronic H. pylori Infection -- Part V Disease -- 16 Synopsis of H. pylori-Associated Diseases -- 17 Atrophic Gastritis and Intestinal Metaplasia -- 18 Functional Dyspepsia -- 19 Peptic Ulcer -- 20 Gastric Extranodal Marginal Zone B-Cell Lymphoma of MALT -- 21 Gastric Cancer: Synopsis and Epidemiology of Gastric Cancer -- 22 Gastric Cancer: Genetic Alternations Induced by H. pylori Infection: The Role of Activation- Induced Cytidine Deaminase -- 23 Gastric Cancer: Epigenetic Mechanisms: Aberrant DNA Methylation and Dysregulation of MicroRNA -- 24 Gastric Cancer: H. pylori and Macrophage Migration Inhibitory Factor -- 25 Gastric Cancer: Epithelial Mesenchymal Transition -- 26 Gastric Cancer: ABO Blood Type -- 27 Gastric Cancer: First Relatives of Gastric Cancer -- 28 H. pylori Infection-Negative Gastric Cancer -- 29 Gastroesophageal Reflux Disease -- 30 NSAID-Induced Gastropathy and H. pylori Infection -- 31 Extraintestinal Manifestations of H. pylori Infection: H. pylori- Associated Iron-Deficiency Anemia -- 32 Extraintestinal Manifestations of H. pylori Infection: Idiopathic Thrombocytopenic Purpura -- 33 Extraintestinal Manifestations of H. pylori Infection: Heart Disease -- 34 Extraintestinal Manifestations of H. pylori Infection: Asthma and Allergic Disorders -- Part VI Antibiotic Resistance -- 35 Synopsis of Antimicrobial Resistance -- 36 Clarithromycin -- 37 Amoxicillin -- 38 Fluoroquinolone -- 39 Metronidazole -- Part VII Treatment -- 40 Synopsis of Antibiotic Treatment -- 41 Triple Therapy -- 42 Quadruple Therapy -- 43 Sequential Therapy -- 44 Concomitant Therapy and Hybrid Therapy -- 45 Tailored Therapy Based on Antibiotic Resistance -- 46 Levofloxacin/Moxifloxacin or Rifabutin-Based Triple Therapy -- 47 Probiotics -- 48 Treatment Guidelines -- 49 Gastric Cancer Screening -- 50 Recrudescence and Reinfection After H. pylori Eradication Treatment -- Part VIII Consequences of H. pylori Eradication -- 51 Peptic Ulcer Disease -- 52 Atrophic Gastritis and Intestinal Metaplasia -- 53 Gastric Cancer -- 54 Extraintestinal Manifestations Depending on Sex and Age -- Part IX The Effect of H. pylori Infection and its Eradication on the Gastric Microbiota -- 55 The Effect of H. pylori Infection on theGastric Microbiota -- 56 The Effect of H. pylori Eradication on the Gastric Microbiota -- Part X Animal Model -- 57 Animal Models of H. pylori Infection.