Section One: Cultural and Social Aspects of Saffron -- 1. Saffron and Folklore -- 2. Saffron and Religions 3. Saffron in the Ancient History of Iran -- Section Two: Saffron Production -- 4. Evolution, Botanical and Agricultural Characteristics of Saffron (Crocus sativus L.) and Related Species -- 5. Soil Conditions for Sustainable Saffron Production -- 6. Water Requirement of Saffron -- 7. Saffron Seeds- The Corm -- 8. Advances in Modeling Saffron Growth and Development at Different Scales -- 9. Saffron Crop Protection -- 10. Ecophysiology of Saffron -- 11. Emerging Innovation in Saffron -- Section Three: Genetics and Biotechnology of Saffron -- 12. Molecular Biology and Genetics of Crocus sativus L. -- 13. Tissue and Cell Culture of Saffron -- 14. Secondary Metabolites in Saffron -- Section Four: Saffron Processing -- 15. Dehydration of Saffron Stigmas -- 16. Assessment and Monitoring of Saffron Microbiological Criteria -- 17. Saffron Adulteration -- Section Five: Economy and Trade of Saffron -- 18. Saffron Cultivation: An Economic Analysis -- 19. Saffron Marketing: Challenges and Opportunities -- 20. Environmental-Economic Analysis of Saffron Production with the Emphasis of Energy, Environmental Impacts and Ecosystem Functions -- Section Six: Saffron and Health -- 21. History of Saffron in Medicine -- 22. Phytochemistry of Saffron -- 23. Saffron in Traditional Medicine -- 24. The Effectiveness of Saffron (Crocus sativus L.) on Memory Function, Learning Ability and Epilepsy -- 25. Antidepressant and Antianxiety Properties of Saffron -- 26. Saffron (Crocus sativus L.) and its Constituents; their Anti-Inflammatory and Immunomodulatory Effects -- 27. Cardiovascular Effects of Saffron and its Active Constituents -- 28. Saffron (Crocus sativus L.) and its Main Constituents, their Effect on Respiratory System -- 29. Saffron in Metabolic Disorders -- 30. Available Saffron Formulations and Patents