Cover image for Intrinsically Disordered Proteins Studied by NMR Spectroscopy
Title:
Intrinsically Disordered Proteins Studied by NMR Spectroscopy
Author:
Felli, Isabella C. editor.
ISBN:
9783319201641
Edition:
1st ed. 2015.
Physical Description:
XIII, 421 p. 111 illus., 98 illus. in color. online resource.
Series:
Advances in Experimental Medicine and Biology, 870
Contents:
Nuclear Magnetic Resonance and Bioinformatics Studies on Intrinsically Disordered Proteins -- Structure and Dynamics of Intrinsically Disordered Proteins -- NMR methods for the study of IDP structure, dynamics and interactions: general overview and practical guidelines -- Ensemble Calculation for IDPs Using NMR Parameters -- NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins -- Recombinant IDPs for NMR: Tips and Tricks -- Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an "Elephant and Blind Men" Situation -- Application of SAXS for the Structural Characterization of IDPs -- Bioinformatics Approaches for Predicting Disordered Protein Motifs -- Towards Understanding Protein Disorder In-Cell -- The Protein Ensemble Database -- Order and Disorder in the Replicative Complex of Paramyxoviruses -- Druggability of Intrinsically Disordered Proteins -- Beta Amyloid Hallmarks: From Intrinsically Disordered Proteins to Alzheimer's Disease.
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