A historical perspective on experimental and clinical islet transplantation / A. M. James Shapiro -- Hypoglycaemia in type 1 diabetes : the need for a new approach / Stephanie A. Amiel -- Patient selection and assessment : an endocrinologist's perspective / Peter A. Senior -- The surgical aspects of pancreas procurement for pancreatic islet transplantation / Neal R. Barshes. [et al.] -- Pancreas preservation for islet isolation / Mohammadreza Mirbolooki and Jonathan R.T. Lakey -- Aspects and challenges of islet isolation / Mohammadreza Mirbolooki. [et al.] -- Percutaneous portal vein access : radiological aspects / Richard J. Owen -- Care of the islet transplant recipient : immunosuppressive management and complications / Raquel N. Faradji. [et al.] -- Islet graft monitoring and imaging / Christian Toso and Thierry Berney -- Metabolic measures of the islet function and mass after islet transplantation / R. Paul Robertson -- Challenges in setting up a new islet transplant program / Paul R.V. Johnson -- Key factors to consider in setting up clinical trials in islet cell transplantation : a nursing coordinator's perspective / Barbara S. DiMercurio -- Clinical outcomes and future directions in islet transplantation / Faisal Al-Saif and A.M. James Shapiro -- Culture and transportation of human islets between centers / Hiorhito Ichii. [et al.] -- Development and application of contemporary immunosuppression in human islet transplantation / Dixon B. Kaufman -- Pig islet xenotransplantation--update and context / Daniel R. Salomon -- Approaches to [beta]-cell regeneration and neogenesis / Susan C. Campbell and Wendy Macfarlane -- Stem cell approaches for [beta]-cell replacement / Enrique Roche and Bernat Soria -- Diabetes gene therapy / Peter S. Chapman and James A.M. Shaw.