chapter 1 Redox Regulation as an Underlying Factor in Health and Disease -- chapter 2 Diet and Lifestyle in Cancer Prevention -- chapter 3 The Gene Regulatory Mechanism of Thioredoxin and Thioredoxin Binding Protein-2/VDUP1 in Cancer Prevention -- chapter 4 Coenzyme Q10, Free Radicals, and Heart Disease / chapter 5 Wine, Alcohol, and a Healthy Heart / chapter 6 Diabetes Treatment by Alpha-Lipoic Acid: Modulation of Glucose Uptake and Adipocyte Differentiation -- chapter 7 The Mechanism of Immune Suppression by GIF and Cysteinylated MIF at Cys-60 -- chapter 8 Role of Free Radicals in Cellular Damage and Its Modification by Antioxidants: Implications for Cancer Therapy -- chapter 9 Free Radicals, Cigarette Smoke, and Health Scavenging Effects of Pycnogenol® on Free Radicals Generated from Cigarette Smoke and Its Detoxification Effects -- chapter 10 Free Radical Scavengers and Neuroprotection -- chapter 11 Oxidative Adaptation in Aging and Alzheimer’s Disease: The Roles of Amyloid and Tau -- chapter 12 Coenzyme Q10 Stabilizes Mitochondria in Parkinson’s Disease -- chapter 13 The In Vitro and In Vivo Molecular Mechanisms of Neuroprotection by the Major Green Tea Polyphenol, (–)-Epigallocatechin-3-gallate, with Special Reference to Parkinson’s Disease -- chapter 14 Kainic-Acid-Induced Neurotoxicity: Involvement of Free Radicals -- chapter 15 Prevention of Cerebral Oxidative Stress Using Traditional Chinese Medicines: A Model of Antioxidant-Based Composite Formula -- chapter 16 Analysis of the Oxidative Stress State in Disease Development of Senescence-Accelerated Mouse -- chapter 17 The Antioxidant Evolution: From Free Radical Scavenging to the Antioxidant Network and Gene Regulation by Flavonoids and Bioflavonoid-Rich Extracts from Pine Bark and Gingko Biloba Leaf -- chapter 18 New Horizons in Vitamin E Research / chapter 19 Gastrointestinal Inflammatory Diseases: Role of Chemokine / chapter 20 Oxidative Stress Involvement in Diabetic Nephropathy and Its Prevention by Astaxanthin -- chapter 21 Preventive and Therapeutic Effects of Plant Polyphenols through Suppression of Nuclear Factor-Kappa B -- chapter 22 Ascorbic Acid and Oxidative Damage to DNA: Interrelationships and Possible Relevance to Lifestyle-Related Diseases -- chapter 23 The Role of Lipid Peroxidation in Chromosomal DNA Fragmentation Associated with Cell Death Induced by Glutathione Depletion -- chapter 24 Antioxidant Properties of Select Indian Medicinal Plants in Relation to Their Therapeutic Effects -- chapter 25 Antioxidant Activity of Tendai-Uyaku Extract -- chapter 26 Detection of Active Oxygen Species in the Decomposition Process of Peroxovanadium (V) Complexes -- chapter 27 Structural Determination and Antioxidative Activity of Oxidation Products of Flavonoids with Reaction Oxygen Species -- chapter 28 Reactivity of Anthocyanin toward Reactive Oxygen and Reactive Nitrogen Species.