1. Prefiltration in biopharmaceutical processes / George T. Quigley -- 2. Charge modified filter media / Eugene A. Ostreicher, Todd E. Arnold, and Robert S. Conway -- 3. Filter Designs / Suraj B. Baloda -- 4. Pore Sizes and distributions / C. Thomas Badenhop -- 5. Concerning mechanisms of particle removal by filters / Theodore H. Meltzer and Maik W. Jornitz -- 6. Microbiological considerations in the selection and validation of filter sterilization / James A. Akers -- 7. Filter sizing : the requirements and their attainment / Theodore H. Meltzer and Maik W. Jornitz -- 8. Filter housings in the biopharmaceutical industry / Barry Bardo -- 9. Stainless steel application and fabrication in the biotech industry / Joe Manfredi -- 10. Protein adsorption by polymeric filters / Theodore H. Meltzer -- 11. The filter integrity tests / Theodore H. Meltzer, Russell E. Madsen, and Maik W. Jornitz -- 12. Filter manufacture quality assurance and validation / Maik W. Jornitz and Theodore H. Meltzer -- 13. Validation of the filter and of the filtration process / Paul S. Stinavage -- 14. Extractables and leachables evaluations for filters / Raymond H. Colton and Denise G. Bestwick -- 15. Endotoxin, limulus amebocyte lysate, and filter applications / Ron Berzofsky -- 16. Limulus amebocyte lysate assays and filter applications / Marilyn J. Gould -- 17. Media and buffer filtration implications / Maik W. Jornitz and Theodore H. Meltzer -- 18. Downstream processing / Uwe Gottschalk -- 19. Crossflow filtration / Michael Dosmar and Steven Pinto -- 20. Ensuring safety of biopharmaceuticals : virus and prion safety considerations / Hazel Aranha --

21. A rapid method for purifying Escherichia coli [beta]-Galactosidase using gel-filtration chromatography / Lynn P. Elwell -- 22. Membrane chromatography / Jeffrey Mora and Sherri Dolan -- 23. Expanded polytetrafluoroethylene membranes and their applications / Michael Wikol ... [et al.] -- 24. Air filtration applications in the pharmaceutical industry / Monica Cardona and Glenn Howard -- 25. Sterility testing by filtration in the pharmaceutical industry / Olivier Guňec -- 26. Bacterial biofilms in pharmaceutical water systems / Marc W. Mittelman -- 27. Steam sterilization of filters / Simon A. Cole -- 28. Ozone applications in biotech and pharmaceuticals / Joe Manfredi.