Cover image for Handbook of drug screening
Title:
Handbook of drug screening
Author:
Seethala, Ramakrishna, 1947-
ISBN:
9781420061697
Edition:
2nd ed.
Publication Information:
New York : Informa Healthcare, c2009.
Physical Description:
xiii, 489 p. : ill.
Series:
Drugs and the pharmaceutical sciences ; 196
Series Title:
Drugs and the pharmaceutical sciences ; 196
Contents:
1. Key factors for successful high-throughput screening / John G. Houston -- 2. Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- 3. Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- 4. Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- 5. Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- 6. Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic --

7. Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang -- 8. Emerging novel high-throughput screening technologies for cell-based assays / ILona Kariv ... [et al.] -- 9. In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- 10. Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- 11. Protein kinases and phosphatases / Pirthipal Singh -- 12. MicroRNA strategies in drug discovery / Wishva B. Herath ... [et al.] -- 13. Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli --

14. Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan -- 15. High-content screening with a special emphasis on cytotoxicity and cell health measurements / Ralph J. Garippa and Ann F. Hoffman -- 16. Effective application of drug metabolism and pharmacokinetics in drug discovery / Sharon Diamond and Swanny Yeleswaram -- 17. Compound management for drug discovery : an overview / Moneesh Chatterjee and Martyn N. Banks -- 18. Practical approach to quantitative high throughput screening / Wei Zheng, Ke Liu, and James Inglese -- 19. Enabling the large-scale analysis of quantitative high-throughput screening data / Noel T. Southall ... [et al.] -- 20. Application of nanobiotechnologies for drug discovery / K.K. Jain.
Holds:
Copies:

Available:*

Library
Material Type
Item Barcode
Shelf Number
Status
Item Holds
Searching...
E-Book 289758-1001 ONLINE
Searching...

On Order