Cover image for Neglected tropical diseases and phytochemicals in drug discovery
Title:
Neglected tropical diseases and phytochemicals in drug discovery
Author:
Egbuna, Chukwuebuka, editor.
ISBN:
9781119617143

9781119617150

9781119617112
Physical Description:
1 online resource (xxviii, 593 pages) : illustrations (chiefly color), color maps
Contents:
Epidemiology of neglected tropical diseases / Kurubaran Ganasegeran -- Neglected tropical diseases, phytochemicals, protein targets and mechanisms in drug discovery / Lalit R. Samant -- Novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis (African sleeping sickness and Chagas disease) and schistosomiasis / Abeer M. El Sayed -- Herbal, nutritional and traditional remedies for giardiasis : phytochemicals as drug candidates / Samrat Bhattacharyya -- Antiprotozoal activity of phytochemicals against Entamoeba histolytica, the causative agent of amoebiasis / Goutam Jena -- Anti-leishmanial potentials of phytochemicals / Shahira Mohamed Ezzat -- Prospects of phytochemicals in the treatment of helminthiasis / Muhammad Akram -- Efficacy of phytochemicals of medicinal plants for the treatment of human echinococcosis : echinococcal disease, hydatidosis or hydatid disease drug discovery / Charles Oluwaseun Adetunji -- Filaricidal activity of phytochemicals against lymphatic filariasis / Sharangouda J. Patil -- Dracunculiasis (Guinea worm disease) and phytochemicals in drug discovery / Muhammad Akram -- Medicinal potentials of phytochemicals as a source of drugs for the treatment of onchocerciasis (river blindness) / Chandrashekar Srinivasa -- Foodborne trematodiases and phytochemicals / Ramith Ramu -- Bacteriocidal effects of phytochemicals on Mycobacterium ulcerans, the causative agents of buruli ulcer / Alloysius Chibuike Ogodo -- Bacteriocidal effects of phytochemicals on Mycobacterium leprae, the causative agent of leprosy / Chukwuebuna Egbuna -- Medicinal plants and phytochemicals effective against chlamydia trachomatis, the causative agent of trachoma / Habibu Tijjani -- Yaws (endemic treponematoses) drug discovery from phytochemicals : an informatics protocol for drug target identification to phytochemical inhibitor screening and validation / Zarrin Basharat -- Dengue fever : a brief overview and insights into the potential applicability of phytochemicals in its management / Muhammad Akram -- Medicinal potentials of phytochemicals for the management of rabies / Chandan Shivamallu -- Roles of medicinal plants in the diagnosis and treatment of eumycetoma / Chinaza Godswill Awuchi -- Role of phytochemicals in the treatment of ectoparasitic infections : scabies and myiasis / Santwana Palai -- Malaria and recent developments in antimalarial drugs / Mithun Rudrapal -- Therapeutic potentials of phytochemicals against mycobacterium tuberculosis, the causative agents of tuberculosis / Alloysius Chibuike Ogodo.
Abstract:
NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.
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John Wiley and Sons
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E-Book 597026-1001 RC961 .N4383 2022
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