Introduction -- Prevalence and Aetiology of Enamel Defects -- Syndromes and Diseases Associated with Enamel Defects -- Molar Incisor Hypomineralisation: Prevalence and Diagnosis -- Aetiology -- Impact on Enamel Structure -- Amelogenesis Imperfecta and Other Genetic Enamel Defects -- Syndromes and Diseases Associated with Enamel Defects -- Impact of Defective Enamel on Quality of Life -- Examination and Planning Immediate and Long Term Treatment -- Managing Sensitivity and Prevention of Dental Caries in Teeth with Enamel Defects -- Restorative Management of Primary Teeth -- Restorative and Orthodontic Management of Permanent Teeth from Eruption to the Definitive Restorations -- Improving the Enamel - What are the Possibilities and the Future -- Conclusion.