Title:
Chirality in biological nanospaces reactions in active sites
Author:
Nandi, Nilashis.
ISBN:
9781439840030
Publication Information:
Boca Raton : CRC Press, 2012.
Physical Description:
xvi, 193, [10] p. of plates : ill. (some col.).
Contents:
ch. 1. Introduction -- ch. 2. Chiral discrimination in the active site of oxidoreductases -- ch. 3. Transferases and chiral discrimination -- ch. 4. Influence of chirality on the hydrolysis reactions within the active site of hydrolases -- ch. 5. Influence of chirality on the reactions in the active site of lyases -- ch. 6. Chiral discrimination in the active site of ligases -- ch. 7. Summary and future directions.
Abstract:
"Vital life processes occur within the active sites of large biological macromolecules such as proteins, nucleic acids, and lipids. These nanodimensional structures greatly accelerate biological reactions. The chirality of the reactants also has a strong influence on the process, but its importance in such biological reactions has only recently begun to be understood. This book explores the influence of chirality on reaction mechanisms in such biological nanospaces. The text addresses the influence of the chirality of amino acid and sugar in the active sites of transferase, oxidoreductases, hydrolases, lysases, isomerase, ligases, and other systems. It also covers ribosomal architecture"--Provided by publisher.
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