Title:
Genetic toxicology and cancer risk assessment
Author:
Choy, Wai Nang, 1946-
ISBN:
9780203904237
Publication Information:
New York : Marcel Dekker, c2001.
Physical Description:
xiii, 390 p. : ill. ; 24 cm.
Contents:
1. Human cancer genetics / Jason W. Barlow and David Malkin -- 2. Genetic toxicity tests for predicting carcinogenicity / Errol Zeiger -- 3. Genotoxic and nongenotoxic mechanisms of carcinogenesis / Wai Nang Choy -- 4. Structure-activity relationship (SAR) and its role in cancer risk assessment / David Y. Lai and Yin-tak Woo -- 5. Regulatory genetic toxicology tests / Wai Nang Choy -- 6. Complementary gentic toxicology assays / B. Bhaskar Gollapudi -- 7. The mouse lymphoma assay (MLA) using the Microwell method / Masamitsu Honma and Toshio Sofuni -- 8. The in vitro micronucleus assay / Marilyn J. Aardema and Micheline Kirsch-Volders -- 9. ICH guidelines on genotoxicity and carcinogenicity : scientific background and regulatory practice / Lutz M¿ller, Peter Kasper and Leonard Schechtman -- 10. New OECD genetic toxicology guidelines and interpretation of results / Michael C. Cimino --
11. Dose-response relationships in chemical carcinogenesis and cancer risk assessment / Werner K. Lutz -- 12. Molecular epidemiology and biomarkers / Jia-Sheng Wang, Jonathan M. Links, John D. Groopman -- 13. Quantitative cancer risk assessment of nongenotoxic carcinogens / Anna M. Fan and Robert A. Howd -- 14. Risk assessment of genotoxic carcinogens / Lauren Zeise -- 15. Biologically based cancer risk assessment models / Suresh H. Moolgavkar.
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