Cover image for BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug Discovery
Title:
BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug Discovery
Author:
Sullivan, Ryan J. editor.
ISBN:
9781493921430
Edition:
1st ed. 2015.
Physical Description:
VIII, 204 p. 26 illus., 21 illus. in color. online resource.
Series:
Cancer Drug Discovery and Development, 82
Contents:
Melanoma: Historical Context -- Melanoma Pathogenesis -- Molecular Diagnostics and Tumor Mutational Analysis -- Clinical Utility of BRAF-targeted therapy in Melanoma -- The Ethics of Randomized Trials in Oncology -- Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma -- Targeting the cell cycle and p53 in combination with BRAF-directed therapy -- Combination BRAF-directed therapy and immunotherapy -- Moving Forward: Making BRAF-Targeted Therapy Better.
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