1. Rationale for sustained-release injectable products / Judy H. Senior -- 2. Product development principles of sustained-release injectable formulations / Michael Radomsky -- 3. Commercial sustained-release injectable formulations by encapsulation / Mantripragada B. Sankaram -- 4. Insoluble salt forms and drug complexes / Judy H. Senior -- 5. Non-aqueous solutions and suspensions as sustained-release injectable formulations / Sudaxshina Murdan and Alexander T. Florence -- 6. Emulsions for sustained drug delivery / Maninder Hora and Stephen Tuck -- 7. Liposomes for local sustained drug release / Christien Oussoren ... [et al.] -- 8. Synthetic polymers for nanosphere and microsphere products / Michael Radomsky, LinShu Liu, and Taro Iwamoto -- 9. Nano/microspheres from natural polymers / LinShu Liu and Joseph Kost -- 10. In situ gelling systems / Arthur J. Tipton and Richard L. Dunn -- 11. Guidelines for selecting sustained-release technology / Praveen Tyle, Ge Chen, and Leo Pavliv -- 12. Veterinary sustained-release parenteral products / Jung-Chung Lee and Michael Putnam -- 13. Applications in vaccine and gene delivery / Maninder Hora and Ramachandran Radhakrishnan -- 14. Microspheres for protein and peptide delivery : applications and opportunities / Paul A. Burke and Scott D. Putney -- 15. Toxicology and biocompatibility evaluation of microsphere and liposome sustained-release drug delivery systems / M. Gary I. Riley and Scott D. Putney -- 16. Scale-up, validation, and manufacturing of microspheres / Kunio Kawamura -- 17. Quality control methods and specifications / Johanna K. Lang -- 18. Regulatory perspectives and product approval processes / Natalie L. McClure.