Weeds negatively impact crop yields, the quality of agricultural produce, the health of livestock and ecosystems, and various aspects of human life. Despite significant expenditures of time, money, and resources by agricultural producers, land managers, and the general public, weeds persist. Developing new methods for protecting crops and the environment requires a thorough understanding of the persistence mechanisms of weeds. In Persistence Strategies of Weeds, an international team of expert authors provide detailed information on weed seed biology, identify the vulnerabilities of different weeds, and address the underlying issues behind the problem of weed persistence despite various management methods including herbicides. Presenting a comprehensive approach to the subject, the authors describe what is already understood about weed persistence and what yet needs to be determined. Topics include the role of seed production, dissemination, seed banks, the physiology and genetics of seed dormancy, the influence of agronomic practices, seed longevity, vegetative propagation, allelopathy, predation, soil microbes, weed evolution, and more.