Title:
Molecular biology in medicinal chemistry
Author:
Dingermann, Theodor.
ISBN:
9783527304318
Publication Information:
Weinheim : Wiley-VCH, c2004.
Physical Description:
xxi, 413 s. : res. ; 24 cm.
Series:
Methods and principles in medicinal chemistry ; v. 21
Series Title:
Methods and principles in medicinal chemistry ; v. 21
Contents:
Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.
Abstract:
Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
Holds:
Copies:
Available:*
Library | Material Type | Item Barcode | Shelf Number | Status | Item Holds |
|---|---|---|---|---|---|
Searching... | Book | 7.2/12/402241 | QV 744 M5926 2004 V.21 | Searching... | Searching... |