Search Results for Pharmacokinetics - Narrowed by: Electronic Library

Pharmacokinetics

2024-11-03T07:13:47Z

Author Gibaldi, Milo. Perrier, Donald.
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Basic Pharmacokinetics

2024-11-03T07:13:47Z

Author Jambhekar, Sunil. Breen, Philip J.
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Electronic Access EBSCOhost http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=444415
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Basic pharmacokinetics

2024-11-03T07:13:47Z

Author Jambhekar, Sunil. Breen, Philip J.
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Electronic Access EBSCOhost http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=281478
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Computational pharmacokinetics

2024-11-03T07:13:47Z

Author Kl̃lň, Anders.
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Comparative pharmacokinetics

2024-11-03T07:13:47Z

Author Riviere, J. Edmond (Jim Edmond), author. Wiley InterScience (Online service)
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Electronic Access Wiley InterScience An electronic book accessible through the World Wide Web; click for information ebrary http://site.ebrary.com/id/10577561
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Clinical pharmacokinetics handbook

2024-11-03T07:13:47Z

Author Bauer, Larry A.
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Electronic Access Subscription required
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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

2024-11-03T07:13:47Z

Author Vinks, Alexander A. editor. Derendorf, Hartmut. editor. Mouton, Johan W. editor. SpringerLink (Online service)
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Electronic Access https://doi.org/10.1007/978-0-387-75613-4
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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

2024-11-03T07:13:47Z

Author Rudek, Michelle A. editor. Chau, Cindy H. editor. Figg, William D. editor. McLeod, Howard L. editor. SpringerLink (Online service)
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Electronic Access https://doi.org/10.1007/978-1-4614-9135-4
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Pharmacokinetics and metabolism in drug design

2024-11-03T07:13:47Z

Author Smith, Dennis A.
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Electronic Access Wiley http://dx.doi.org/10.1002/9783527645763 Wiley InterScience http://dx.doi.org/10.1002/9783527645763
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Drug Metabolism and Pharmacokinetics Quick Guide

2024-11-03T07:13:47Z

Author Khojasteh, Siamak Cyrus. author. Wong, Harvey. author. Hop, Cornelis E.C.A. author. SpringerLink (Online service)
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Electronic Access http://dx.doi.org/10.1007/978-1-4419-5629-3
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Pharmacology & Pharmacokinetics A Basic Reader

2024-11-03T07:13:47Z

Author Tomlin, Mark. editor. SpringerLink (Online service)
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Electronic Access http://dx.doi.org/10.1007/978-1-84996-146-2
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Pharmacokinetics and pharmacodynamics of abused drugs

2024-11-03T07:13:47Z

Author Karch, Steven B.
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Pharmacokinetics and pharmacodynamics of abused drugs

2024-11-03T07:13:47Z

Author Karch, Steven B.
Preferred Shelf Number ONLINE(342836.1)
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Pharmacokinetics and metabolism in drug design

2024-11-03T07:13:47Z

Author Smith, Dennis A. Waterbeemd, Han van de. Walker, Don K. John Wiley & Sons.
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Electronic Access John Wiley http://dx.doi.org/10.1002/3527608222 http://www3.interscience.wiley.com/cgi-bin/bookhome/112682970
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Handbook of anticancer pharmacokinetics and pharmacodynamics

2024-11-03T07:13:47Z

Author Figg, William D. McLeod, Howard L.
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Electronic Access EBSCOhost http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=117434
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Pharmacokinetics in drug discovery and development

2024-11-03T07:13:47Z

Author Schoenwald, Ronald D.
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Pharmacokinetics and metabolism in drug design

2024-11-03T07:13:47Z

Author Smith, Dennis A. Van de Waterbeemd, Han. Walker, Don K. John Wiley & Sons.
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Electronic Access John Wiley http://dx.doi.org/10.1002/3527600213 MyiLibrary, Table of contents http://www.myilibrary.com?id=55765&ref=toc
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Pharmacokinetics of Selected Antibacterial Agents

2024-11-03T07:13:47Z

Author Dalhoff,A.
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Electronic Access http://content.karger.com/ProdukteDB/produkte.asp?Aktion=showproducts&searchWhat=books&searchParm=toc&ProduktNr=223293
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Aspirin therapeutic uses, adverse effects, and pharmacokinetics

2024-11-03T07:13:47Z

Author Demir, Dilan M.
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Electronic Access EBSCOhost http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=564943
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Mass spectrometry in drug metabolism and pharmacokinetics

2024-11-03T07:13:47Z

Author Ramanathan, Ragu. Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470409817
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Pharmacokinetics in Drug Development Advances and Applications, Volume 3

2024-11-03T07:13:47Z

Author Bonate, Peter L. editor. Howard, Danny R. editor. SpringerLink (Online service)
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Electronic Access http://dx.doi.org/10.1007/978-1-4419-7937-7
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Drug disposition and pharmacokinetics from principles to applications

2024-11-03T07:13:47Z

Author Curry, Stephen H. Whelpton, Robin. Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470665190
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Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology

2024-11-03T07:13:47Z

Author Han, Chao. Davis, Charles B. (Charles Baldwin) Wang, Binghe, PhD. Wiley InterScience (Online service)
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Electronic Access Ebook Library http://public.eblib.com/EBLPublic/PublicView.do?ptiID=479843 John Wiley http://dx.doi.org/10.1002/9780470574898 MyiLibrary, Table of contents http://www.myilibrary.com?id=268490&ref=toc
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Metabolism, pharmacokinetics and toxicity of functional groups Impact of chemical building blocks on ADMET

2024-11-03T07:13:47Z

Author Alexander, Alex. Smith, Dennis A. Beaumont, Kevin. Kalgutkar, Amit S., 1965- Walker, Don K.
Preferred Shelf Number ONLINE(344111.1)
Electronic Access http://dx.doi.org/10.1039/9781849731102
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Modeling in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Homogeneous and Heterogeneous Approaches

2024-11-03T07:13:47Z

Author Macheras, Panos. author. Iliadis, Athanassios. author. SpringerLink (Online service)
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Electronic Access http://dx.doi.org/10.1007/0-387-31910-7
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Pharmacokinetics and pharmacodynamics of biotech drugs principles and case studies in drug development

2024-11-03T07:13:47Z

Author Meibohm, Bernd. Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9783527609628 http://www3.interscience.wiley.com/cgi-bin/bookhome/113455368
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Optimizing Pharmacotherapy in Older Patients An Interdisciplinary Approach

2024-11-03T07:13:47Z

Author Cherubini, Antonio. editor. Mangoni, Arduino A. editor. O'Mahony, Denis. editor. Petrovic, Mirko. editor. SpringerLink (Online service)
Preferred Shelf Number XX(521833.1)
Electronic Access https://doi.org/10.1007/978-3-031-28061-0
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Curcumin and Neurodegenerative Diseases From Traditional to Translational Medicines

2024-11-03T07:13:47Z

Author Rai, Mahendra. editor. Feitosa, Chistiane M. editor. SpringerLink (Online service)
Preferred Shelf Number XX(522231.1)
Electronic Access https://doi.org/10.1007/978-981-99-7731-4
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Comprehensive Healthcare Simulation: Pharmacy Education, Practice and Research

2024-11-03T07:13:47Z

Author Al-Worafi, Yaser Mohammed. editor. SpringerLink (Online service)
Preferred Shelf Number XX(521591.1)
Electronic Access https://doi.org/10.1007/978-3-031-33761-1
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Familial Endocrine Cancer Syndromes Navigating the Transition of Care for Pediatric and Adolescent Patients

2024-11-03T07:13:47Z

Author Hannah-Shmouni, Fady. editor. SpringerLink (Online service)
Preferred Shelf Number XX(521956.1)
Electronic Access https://doi.org/10.1007/978-3-031-37275-9
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Respiratory Delivery of Biologics, Nucleic Acids, and Vaccines

2024-11-03T07:13:47Z

Author Lam, Jenny. editor. (orcid) Kwok, Philip Chi Lip. editor. SpringerLink (Online service)
Preferred Shelf Number XX(522182.1)
Electronic Access https://doi.org/10.1007/978-3-031-47567-2
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Neural Information Processing 29th International Conference, ICONIP 2022, Virtual Event, November 22-26, 2022, Proceedings, Part V

2024-11-03T07:13:47Z

Author Tanveer, Mohammad. editor. Agarwal, Sonali. editor. Ozawa, Seiichi. editor. Ekbal, Asif. editor. Jatowt, Adam. editor.
Preferred Shelf Number XX(520402.1)
Electronic Access https://doi.org/10.1007/978-981-99-1642-9
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Peri-operative Anesthetic Management in Liver Transplantation

2024-11-03T07:13:47Z

Author Vohra, Vijay. editor. Gupta, Nikunj. editor. Jolly, Annu Sarin. editor. Bhalotra, Seema. editor. SpringerLink (Online service)
Preferred Shelf Number XX(521435.1)
Electronic Access https://doi.org/10.1007/978-981-19-6045-1
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Molecular Imaging and Targeted Therapy Radiopharmaceuticals and Clinical Applications

2024-11-03T07:13:47Z

Author Vallabhajosula, Shankar. author. SpringerLink (Online service)
Preferred Shelf Number XX(521463.1)
Electronic Access https://doi.org/10.1007/978-3-031-23205-3
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Feed additives : aromatic plants and herbs in animal nutrition and health

2024-11-03T07:13:47Z

Author Christaki, Efterpi, editor. Florou-Paneri, Panagiota, editor. Giannenas, Ilias, editor.
Preferred Shelf Number XX(522377.1)
Electronic Access ScienceDirect https://www.sciencedirect.com/science/book/9780128147009
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Lipid-based nanocarriers for drug delivery and diagnosis

2024-11-03T07:13:47Z

Author Shah, Muhammad Raza, author. Imran, Muhammad, author. Ullah, Shafi, author.
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Electronic Access ScienceDirect http://www.sciencedirect.com/science/book/9780323527293 ScienceDirect https://www.sciencedirect.com/science/book/9780323527293
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Nanotechnology methods for neurological diseases and brain tumors : drug delivery across the blood--brain barrier

2024-11-03T07:13:47Z

Author Özdemir, Yasemin Gürsoy, author. Pehlivan, Sibel Bozdag, author. Sekerdag, Emine, author.
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Electronic Access ScienceDirect http://www.sciencedirect.com/science/book/9780128037966 ScienceDirect https://www.sciencedirect.com/science/book/9780128037966
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Serum pharmacochemistry of traditional Chinese medicine : technologies, strategies and applications

2024-11-03T07:13:47Z

Author Wang, Xijun, 1961- editor. Zhang, Aihua (Of National TCM Key Laboratory of Serum Pharmacochemistry), editor. Sun, Hui (Of National TCM Key Laboratory of Serum Pharmacochemistry), editor.
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Electronic Access ScienceDirect http://www.sciencedirect.com/science/book/9780128111475
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Pyrantel parasiticide therapy in humans and domestic animals

2024-11-03T07:13:47Z

Author Marchiondo, Alan A., editor.
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Electronic Access ScienceDirect https://www.sciencedirect.com/science/book/9780128014493
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Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials

2024-11-03T07:13:47Z

Author Kiang, Tony K.L. author. Wilby, Kyle John. author. Ensom, Mary H.H. author. SpringerLink (Online service)
Preferred Shelf Number XX(519368.1)
Electronic Access https://doi.org/10.1007/978-3-319-10527-7
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Evidence-Based Periodontal and Peri-Implant Plastic Surgery A Clinical Roadmap from Function to Aesthetics

2024-11-03T07:13:47Z

Author Chambrone, Leandro. editor. SpringerLink (Online service)
Preferred Shelf Number XX(519439.1)
Electronic Access https://doi.org/10.1007/978-3-319-13975-3
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Pediatric Sedation Outside of the Operating Room A Multispecialty International Collaboration

2024-11-03T07:13:47Z

Author Mason, Keira P. editor. SpringerLink (Online service)
Preferred Shelf Number XX(519517.1)
Electronic Access https://doi.org/10.1007/978-1-4939-1390-9
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Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care

2024-11-03T07:13:47Z

Author Kaye, Alan David. editor. Kaye, Adam M. editor. Urman, Richard D. editor. SpringerLink (Online service)
Preferred Shelf Number XX(520058.1)
Electronic Access https://doi.org/10.1007/978-1-4614-8948-1
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Preventive and Predictive Genetics: Towards Personalised Medicine

2024-11-03T07:13:47Z

Author Grech, Godfrey. editor. Grossman, Iris. editor. SpringerLink (Online service)
Preferred Shelf Number XX(520059.1)
Electronic Access https://doi.org/10.1007/978-3-319-15344-5
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Advances in chromatography

2024-11-03T07:13:47Z

Author Grushka, Eli, editor. Grinberg, Nelu, 1950- editor.
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The organic chemistry of drug design and drug action.

2024-11-03T07:13:47Z

Author Silverman, Richard B., author. Holladay, Mark W., author.
Preferred Shelf Number ONLINE(355830.1)
Electronic Access ScienceDirect http://www.sciencedirect.com/science/book/9780123820303
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Systems biology in drug discovery and development

2024-11-03T07:13:47Z

Author Young, Daniel L., editor. Michelson, Seth, editor. Wiley InterScience (Online service)
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Electronic Access Wiley InterScience An electronic book accessible through the World Wide Web; click for information
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Medical toxicology of drug abuse synthesized chemicals and psychoactive plants

2024-11-03T07:13:47Z

Author Barceloux, Donald G. Wiley InterScience (Online service)
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Electronic Access Wiley InterScience An electronic book accessible through the World Wide Web; click for information
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Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry

2024-11-03T07:13:47Z

Author Peters, Sheila Annie.
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Electronic Access Wiley InterScience An electronic book accessible through the World Wide Web; click for information Wiley http://onlinelibrary.wiley.com/book/10.1002/9781118140291
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ADME-enabling technologies for drug design and development

2024-11-03T07:13:47Z

Author Zhang, Donglu. Surapaneni, Sekhar.
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Electronic Access Wiley InterScience http://dx.doi.org/10.1002/9781118180778
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Lu's basic toxicology fundamentals, target organs, and risk assessment

2024-11-03T07:13:47Z

Author Kacew, Sam. Yi, Py?ng-mu, 1954-
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Herbal medicines development and validation of plant-derived medicines for human health

2024-11-03T07:13:47Z

Author Bagetta, Giacinto.
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ADMET for medicinal chemists a practical guide

2024-11-03T07:13:47Z

Author Tsaioun, Katya. Kates, Steven A., 1961- Wiley InterScience (Online service)
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Electronic Access Ebook Library http://public.eblib.com/EBLPublic/PublicView.do?ptiID=698845 John Wiley http://dx.doi.org/10.1002/9780470915110
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Kinetics of enzyme action essential principles for drug hunters

2024-11-03T07:13:47Z

Author Stein, Ross L. Wiley InterScience (Online service)
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Electronic Access Wiley InterScience An electronic book accessible through the World Wide Web; click for information http://swb.eblib.com/patron/FullRecord.aspx?p=693195
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Mass spectrometry in drug metabolism and disposition basic principles and applications

2024-11-03T07:13:47Z

Author Lee, Mike S., 1960- Zhu, Mingshe.
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470929278 http://public.eblib.com/EBLPublic/PublicView.do?ptiID=675235
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Hydrophilic interaction liquid chromatography (HILIC) and advanced applications

2024-11-03T07:13:47Z

Author Wang, Perry G. He, Weixuan.
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Dyes and drugs new uses and implications

2024-11-03T07:13:47Z

Author Trimm, Harold H. (Harold Henry), 1955- Hunter, William.
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Dermatokinetics of therapeutic agents

2024-11-03T07:13:47Z

Author Murthy, S. Narasimha (Sathyanarayana Narasimha), 1971-
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Modern drug synthesis

2024-11-03T07:13:47Z

Author Li, Jie Jack. Johnson, Douglas S. (Douglas Scott), 1968-
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Electronic Access Wiley InterScience An electronic book accessible through the World Wide Web; click for information Connect to MyiLibrary resource.
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Advances in chromatographic techniques for therapeutic drug monitoring

2024-11-03T07:13:47Z

Author Dasgupta, Amitava, 1958-
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Proteins and peptides pharmacokinetic, pharmacodynamic, and metabolic outcomes

2024-11-03T07:13:47Z

Author Mrsny, Randall J., 1955- Daugherty, Ann L., 1954-
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Preclinical drug development

2024-11-03T07:13:47Z

Author Rogge, Mark C. Taft, David R.
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Metalloproteomics

2024-11-03T07:13:47Z

Author Permi͡akov, E. A. (Evgeniĭ Anatolʹevich) Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470447758
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High-throughput analysis in the pharmaceutical industry

2024-11-03T07:13:47Z

Author Wang, Perry G.
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Prescribing for elderly patients

2024-11-03T07:13:47Z

Author Jackson, S. H. D. (Stephen H. D.) Jansen, Paul A. F. Mangoni, Arduino A. Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470017975
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Drug bioavailability estimation of solubility, permeability, absorption and bioavailability

2024-11-03T07:13:47Z

Author Waterbeemd, Han van de. Testa, Bernard. Wiley InterScience (Online service)
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Electronic Access Ebook Library http://public.eblib.com/EBLPublic/PublicView.do?ptiID=481429 John Wiley http://dx.doi.org/10.1002/9783527623860
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Handbook of drug screening

2024-11-03T07:13:47Z

Author Seethala, Ramakrishna, 1947- Zhang, Litao.
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Drug design of zinc-enzyme inhibitors functional, structural, and disease applications

2024-11-03T07:13:47Z

Author Supuran, Claudiu T., 1962- Winum, Jean-Yves. Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470508169
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Design and analysis of bioavailability and bioequivalence studies

2024-11-03T07:13:47Z

Author Chow, Shein-Chung, 1955- Liu, Jen-pei, 1952-
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Drug-like properties concepts, structure design and methods : from ADME to toxicity optimization

2024-11-03T07:13:47Z

Author Kerns, Edward Harvel. Di, Li.
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Electronic Access ScienceDirect http://www.sciencedirect.com/science/book/9780123695208
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Preclinical development handbook. ADME and biopharmaceutical properties

2024-11-03T07:13:47Z

Author Gad, Shayne C., 1948- Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470249055
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Drug-drug interactions

2024-11-03T07:13:47Z

Author Rodrigues, A. David.
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Antisense drug technology principles, strategies, and applications

2024-11-03T07:13:47Z

Author Crooke, Stanley T.
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Small animal clinical pharmacology

2024-11-03T07:13:47Z

Author Maddison, Jill E., editor of compilation. Page, Stephen W., editor of compilation. Church, David B., editor of compilation.
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Electronic Access ScienceDirect http://www.sciencedirect.com/science/book/9780702028588
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Molecular drug properties measurement and prediction

2024-11-03T07:13:47Z

Author Mannhold, Raimund, 1948-
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Electronic Access Ebook Library http://public.eblib.com/EBLPublic/PublicView.do?ptiID=481318 John Wiley http://dx.doi.org/10.1002/9783527621286 MyiLibrary, Table of contents http://www.myilibrary.com?id=201059&ref=toc ebrary http://site.ebrary.com/id/10577527
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Lipoic acid energy production, antioxidant activity and health effects

2024-11-03T07:13:47Z

Author Patel, Mulchand S. Packer, Lester.
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Statistical and computational pharmacogenomics

2024-11-03T07:13:47Z

Author Wu, Rongling. Lin, Min, 1971-
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Drug metabolism in drug design and development basic concepts and practice

2024-11-03T07:13:47Z

Author Zhang, Donglu. Zhu, Mingshe. Humphreys, W. Griffith. Wiley InterScience (Online service)
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Electronic Access John Wiley http://dx.doi.org/10.1002/9780470191699
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Generic drug product development bioequivalence issues

2024-11-03T07:13:47Z

Author Kanfer, Isadore. Shargel, Leon, 1941-
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Pharmacometrics the science of quantitative pharmacology

2024-11-03T07:13:47Z

Author Ette, Ene I. Williams, Paul J.
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Drug transporters molecular characterization and role in drug disposition

2024-11-03T07:13:47Z

Author You, Guofeng. Morris, Marilyn Emily. Wiley InterScience (Online service)
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Pharmaceutical product development in vitro-in vivo correlation

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Author Chilukuri, Dakshina Murthy. Sunkara, Gangadhar. Young, David, 1952-
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Understanding drug release and absorption mechanisms a physical and mathematical approach

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Author Grassi, Mario, 1954-
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Toxicokinetics and risk assessment

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Author Lipscomb, John C. Ohanian, Edward V.
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Novel anticancer agents strategies for discovery and clinical testing

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Author Adjei, Alex A. Buolamwini, John K.
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Molecular interaction fields applications in drug discovery and ADME prediction

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Author Cruciani, Gabriele.
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Pharmacokinetic profiling in drug research biological, physicochemical, and computational strategies

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Author Lipophilicity Symposium (3rd : 2004 : Swiss Federal Institute of Technology) Testa, Bernard. Wiley InterScience (Online service)
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The process of new drug discovery and development

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Author Smith, Charles G. (Charles Giles) O'Donnell, James, Pharm. D. Smith, Charles G. (Charles Giles). Process of new drug discovery and development.
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Understanding nicotine and tobacco addiction

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Author Symposium on Understanding Nicotine and Tobacco Addiction (2005 : Novartis Foundation) Bock, Gregory. Goode, Jamie. Wiley InterScience (Online service)
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Surface activity in drug action

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Author Srivastava, R. C. Nagappa, A. N.
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Physiologically based pharmacokinetic modeling science and applications

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Author Reddy, Micaela B. John Wiley & Sons.
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Integrated strategies for drug discovery using mass spectrometry

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Author Lee, Mike S., 1960-
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The Organic Chemistry of Drug Design and Drug Action

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Author Silverman, Richard B.
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Phytochemicals mechanisms of action

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Author Meskin, Mark S. International Phytochemical Conference (4th : 2002 : California State Polytechnic University, Pomona)
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A handbook of bioanalysis and drug metabolism

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Author Evans, Gary, 1953-
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High throughput bioanalytical sample preparation methods and automation strategies

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Author Wells, David A.
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Drug bioavailability estimation of solubility, permeability, absorption and bioavailability

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Author Waterbeemd, Han van de. Lennernäs, Hans. Artursson, Per.
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Phytochemicals in nutrition and health

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Author Meskin, Mark S.
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Drug-membrane interactions analysis, drug distribution, modeling

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Author Seydel, J. K. (Joachim Karl) Wiese, Michael, Dr.
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The mechanics of inhaled pharmaceutical aerosols an introduction

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Author Finlay, Warren H.
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Pharmacokinetic optimization in drug research biological, physicochemical, and computational strategies

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Author Lipophilicity Symposium (2nd : 2000 : University of Lausanne) Testa, Bernard. Wiley InterScience (Online service)
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Transport processes in pharmaceutical systems

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Author Amidon, Gordon L. Lee, Ping I., 1948-. Topp, Elizabeth M., 1957-
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Stable isotopes in pharmaceutical research

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Author Browne, Thomas R.
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Metered dose inhaler technology

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Author Purewal, Tol S. Grant, David J. W. (David James William), 1937-
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The organic chemistry of drug design and drug action

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Author Silverman, Richard B.
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Adenosine in the nervous system

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Author Stone, T. W.
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Lithium and the cell pharmacology and biochemistry

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Author Birch, Nicholas J.
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Microsomes, drug oxidations and chemical carcinogenesis. Volume 2

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Author International Symposium on Microsomes and Drug Oxidations (4th : 1979 : Ann Arbor, Mich.) Coon, Minor Jesser, 1921-
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