Molecular biology in medicinal chemistry
tarafından
Dingermann, Theodor.
Başlık
:
Molecular biology in medicinal chemistry
Yazar
:
Dingermann, Theodor.
ISBN
:
9783527304318
Yayın Bilgileri
:
Weinheim : Wiley-VCH, c2004.
Fiziksel Tanımlama
:
xxi, 413 s. : res. ; 24 cm.
Seri
:
Methods and principles in medicinal chemistry ; v. 21
Seri Başlığı
:
Methods and principles in medicinal chemistry ; v. 21
İçerik
:
Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.
Özet
:
Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
Konu Terimleri
:
Kimya, Farmasötik
Moleküler Biyoloji
Genetik Mühendisliği
Chemistry, Pharmaceutical
Molecular Biology
Genetic Engineering
Yazar Ek Girişi
:
Dingermann, Theodor.
Steinhilber, Dieter, 1959-
Folkers, Gerd.
| Kütüphane | Materyal Türü | Demirbaş Numarası | Yer Numarası | [[missing key: search.ChildField.HOLDING]] | Durumu/İade Tarihi |
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| Sağlık Bilimleri Kütüphanesi | Kitap | 7.2/12/402241 | QV 744 M5926 2004 V.21 | | Sağlık Bilimleri Genel Koleksiyon |