Current Massively Parallel Sequencing Technologies: Platforms and Reporting Considerations -- Emerging Next Generation Sequencing Technologies -- Transcriptome Sequencing (RNA-Seq) -- miRNA Expression Assays -- Circulating Tumor Cells: Enrichment and Genomic Applications -- Circulating Cell-free DNA for Molecular Diagnostics and Therapeutic Monitoring -- Genomic Pathology: Training for New Technology -- Implementation of Genomic Sequencing Assays -- Regulatory and Reimbursement Issues in Genomic Testing -- Patents and Proprietary Assays -- Ethical Issues in Clinical Genetics and Genomics -- Transitioning Discoveries from Cancer Genomics Research Laboratories into Pathology Practice -- Bioinformatics Tools in Clinical Genomics -- Next Generation Sequencing for Single Gene Analysis -- Next Generation Sequencing for Gene Panels -- Implementation of Exome Sequencing Assays -- Implementation of Genome Sequencing Assays -- Clinical Information Systems in the Era of Personalized Medicine -- Reporting Clinical Genomic Assay Results and the Role of the Pathologist -- Genomic Applications in Hematologic Oncology -- Genomic Applications in Brain Tumors -- Genomic Applications in Head and Neck Cancers -- Genomic Applications in Breast Carcinoma -- Genomic Applications in Pulmonary Malignancies -- Genomic Applications in Colorectal and Pancreatic Tumors -- Molecular Pathology of Genitourinary Cancers: Translating the Cancer Genome to the Clinic -- Genomic Applications in Gynecologic Malignancies -- Genomic Applications in Epithelial Ovarian Malignancies -- Genomic Applications in Soft Tissue Sarcomas -- Genomic Applications in Inherited Genetic Disorders -- Genomic Applications in Pharmacogenomics -- Sequencing Cell Free DNA in the Maternal Circulation to Screen for Down Syndrome and Other Common Aneuploidies -- Genomic Applications in the Clinical Management of Infectious Diseases. .