Introduction -- Foreword -- Hypertrophic Cardiomyopathy: The Past, The Present, and The Future -- Natural History of Untreated Hypertrophic Cardiomyopathy -- Pathology & Pathophysiology -- Approach to Diagnosis: Echocardiography -- Cardiac MRI in Diagnosis and Management -- Genetics of HCM and Role of Genetic Testing -- Assessment of Heart Failure: Invasive and Non-invasive Methods -- Assessment of Syncope -- Pediatric Diagnosis and Management -- Sudden Cardiac Death Risk Assessment -- Youth and Athletic Screening: Rationale, Methods and Outcome -- Lifestyle Modification: Diet, Exercise, Sports and Other Issues -- Family Screening: Who, When and How -- Medical Therapy: From Beta-Blockers to Disopyramide -- Indications and Outcome of PPM and ICD Placement -- Management of Arrhythmia: Medications, Electrophysiology Studies and Ablation -- Indications for and Individualization of Septal Reduction Therapy -- Surgical Myectomy and Associated Procedures: Techniques and Outcomes -- Alcohol Septal Ablation: Technique and Outcome -- End-Stage Diastolic and Systolic Heart Failure: Evaluation and Timing of Heart Transplantation -- Approach to the Initial and Follow-Up Visits -- Evaluation and Management of Hypertrophic Cardiomyopathy Patients through Noncardiac Surgery and Pregnancy -- Constructing a Hypertrophic Cardiomyopathy Center of Excellence -- Longitudinal Case-Based Presentations in HCM.