Signs and symptoms -- Diagnostic Studies of Pediatric Bone Tumors: Pathology and Imaging -- Basic Principles of Biopsy -- The evaluation of lung nodules in pediatric bone tumors -- Fertility Preservation and Reproductive Health in Pediatric Bone Tumor Patients -- Chemotherapy Regimens for Patients with Newly Diagnosed Malignant Bone Tumors -- Radiation Management -- Histologic Response and Biologic Markers -- Surgical Approach: Limb Salvage Versus Amputation -- Rehabilitation following Orthopaedic Surgery in Children with Bone Tumors -- Patient Navigation of the Pediatric Bone Tumor Patient Across the Continuum of Care -- Psychosocial Effects of Pediatric Bone Tumors and Recommendations for Supportive Care -- Post-therapy surveillance of bone tumors -- Recurrent Bone Tumors -- Novel Therapies on the Horizon -- Survivorship.