Pathophysiology: The target for renal denervation -- Physiological Rationale for Renal Denervation Therapy in Hypertension -- Preclinical Model and Histopathology Translational Medicine and Renal Denervation.- The endpoint on measuring the clinical effects of renal denervation:  What are the best surrogates -- Appraisal of the Clinical Trial Data on Renal Denervation for the Management of Resistant Hypertension -- Catheter-Based Technology Alternatives for Renal Denervation: An Overview -- Medtronic ardian symplicity™ renal denervation devices -- Sympathetic Renal Denervation Using the EnligHTN Multi-electrode Ablation System: The St Jude Experience -- ReCor Medical Paradise® Renal Denervation System -- Therapeutic Intra Vascular Ultrasound (TIVUS) -- The "OneShot" Irrigated Balloon-Mounted Spiral Electrode Renal Denervation Device -- NOVOSTE: The Brachytherapy Approach to Renal Denervation -- Perivascular Renal Denervation (PVRDTM): Chemical Renal Denervation With Micro-doses of Ethanol Using the PeregrineTM Renal Denervation Device -- Vincristine Local Delivery for Renal Artery Denervation.- NephroBlate™ Renal Denervation System: Urologic-nephrologic Based Approach to Resistant Hypertension -- Targeted renal nerve deactivation by neurotropic agents -- Boston Scientific Vessix™ Renal Denervation System -- Radiofrequency and irrigated ablation - principles and potential for renal artery denervation (RDN) in the treatment of resistant arterial hypertension -- Renal denervation: Potential future  implications beyond resistant hypertension -- Renal Denervation for Congestive Heart Failure -- Great myths of blood pressure effect size in renal denervation.- The Potential Role of Catheter-based Renal Sympathetic Denervation in Chronic and End Stage Kidney Disease -- Diabetes and Metabolic Syndrome.-  Obstructive sleep apnea.