PART I Introduction: Definition/Epidemiology of arterial disease -- PART II Normal structure and physiology of the arterial system -- PART III Classification of arterial pathology and clinical manifestations: Atherosclerosis -- Arteriosclerosis -- Disease of Precapillary resistance vessels -- PART IV Pathogenetic mechanisms in arterial disease: Hemodynamic and mechanical factors -- Metabolic factors -- Inflammatory markers -- Neurohormonal interactions -- Mineral-bone/ arterial interactions -- Endothelial function and impairment -- Miscellaneous: Pharmacologic/factors/environmental factors -- PART V Systemic arterial disorders: Arterial aging -- Diabetes mellitus -- Metabolic Syndrome/obesity -- Chronic kidney disease/Renovascular interactions -- Pulmonary Hypertension/Pulmonary vascular interactions -- Systemic  vasculitides -- Genetic/ degenerative disorders -- Hypertension -- Toxemia of pregnancy -- Kidney transplants, both donors and recipients -- PART VI Evaluation procedures: Arterial function -- Renal resistive index -- Retinal microcirculation -- PART VII Therapeutic options: Lifestyle modifications -- Pharmacologic approaches.