Introduction -- Autonomic nervous system of the heart -- Pathophysiology of the autonomic nervous system of the heart -- Tracers for Presynaptic Cardiac Innervation -- Tracers of Adrenergic Receptors -- Tracers of the Parasympathetic System -- Radiopharmaceuticals production under GMP -- Physics of PET-CT and SPECT-CT -- Kinetics & software PET -- SPECT-CT imaging of autonomic innervation in heart diseases -- PET-CT imaging of autonomic innervation in heart diseases -- Imaging ischemic heart disease -- Imaging diabetes mellitus -- Imaging heart failure -- Imaging amyloidosis -- Imaging heart transplantation -- Imaging ventricular arrhythmias -- Guided therapy & imaging -- Imaging the functional brain-heart axis: neurodegenerative diseases -- Imaging the functional brain-heart axis: mental stress & anxiety -- Imaging cardiotoxicity: the effects of chemo- and mono-clonal antibody therapy on autonomic innervation -- Imaging cardiotoxicity: the effect of radiotherapy on autonomic innervation -- Summary and Future Perspectives: PET-MRI Imaging of cardiac Innervation, fluorescence imaging of cardiac innervation -- Epilog -- Index.