Part I. Introduction -- 1. Introduction: Otitis Media Concepts, Facts, and Fallacies; Part II. Concepts and Diagnosis -- 2. Epidemiology of Otitis Media: What Have We Learned in the New Century Global Health Disparities -- 3. Impact of Genetic Background in Otitis Media Predisposition -- 4. Risk Factors for Recurrent Acute Otitis Media and Chronic Otitis Media with Effusion in Childhood -- 5. Microbiology, Antimicrobial Susceptibility and Antibiotic Treatment -- 6. Abnormal Innate and Adaptive Immunity in Otitis Media -- 7. Basic Science Concepts in Otitis Media Pathophysiology and Immunity: Role of Mucins and Inflammation -- 8. Diagnosis of Otitis Media -- Part III. Treatments -- 9. Treatment: Impact of Vaccination and Progress in Vaccine Development -- 10. Antibiotics for Otitis Media: To Treat or Not to Treat -- 11. Tympanostomy Tube Placement for Management of Otitis Media -- 12. Management of Chronic Suppurative Otitis Media -- 13. Otitis Media Complications -- 14. Management of Otitis Mediain Children Receiving Cochlear Implants.