1. Orphan Lung Diseases: From definition to organisation of Care -- 2. The Challenge of clinical research in orphan lung diseases -- 3. Chronic bronchiolitis in adults -- 4. Diffuse bronchiectasis of genetic origin -- 5. Allergic bronchopulmonary mycosis -- 6. Orphan Tracheopathies -- 7. Amyloidosis and the respiratory tract -- 8. Churg-Strauss syndrome: A clinical and therapeutic approach -- 9. Granunomatosis with polyangiitis (Wegener's granylomatosis) -- 10. Alveolar Hemorrhage -- 11. Pulmonary Involvement in Takayasu Arteritis and Behçet Disease -- 12. Pulmonary vascular manifestations of hereditary hemorrhagic -- 13. Hepatopulmonary syndrome -- 14. Non-Langerhans cell histiocytosis -including Erdheim-Chester disease- and the lung -- 15. Idiopathic eosinophilic pneumonia -- 16. Multiple cystic lung disease -- 17. Lymphangioleiomyomatosis -- 18. Pulmonary alveolar Proteinosis -- 19. Exogenous lipoid pneumonia -- 20. Pulmonary alveolar microlithiasis -- 21. Pulmonary Fibrosis and the many faces of UIP -- 22. The syndrome of combined pulmonary fibrosis and emphysema -- 23. Non-specific, Unclassifiable, and Rare Idiopathic Interstitial Pneumonia -- 24. Organizing Pneumonias -- 25. Interstitial lung disease in systemic sclerosis -- 26. Interstitial lung disease in connective tissue diseases other than systemic sclerosis -- 27. Interstitial Lung Disease in Undifferentiated Forms of Connective Tissue Disease -- 28. Langerhans cell Granulomatosis and smoking-related interstitial lung diseases -- 29. Rare causes and the spectrum of hypersensitivity penumonitis -- 30. Chronic beryllium disease and other insterstitial lung diseases of occupational origin -- 31. Lymphoproliferative lung disorders -- 32.  Pulmonary manifestations of hematological malignancies -- 33. Pulmonary hypertension in orphan lung diseases -- 34. Orphan and rare drug-induced and iatrogenic respiratory disease -- 35. From cancer mimicking orphan lung disease to orphan thoracic oncology -- 36. Rare Diffuse lung diseases of genetic origin.