Introduction -- Causes of Anemia in Critically Ill Patients -- Red Blood Cell Transfusion Trigger in Sepsis -- Red Blood Cell Transfusion Trigger in Cardiac Disease -- Red Blood Cell Transfusion Trigger in Cardiac Surgery.- Red Blood Cell Transfusion Trigger in Brain Injury.- Red Blood Cell Transfusion in the Elderly -- ScvO2 as an Alternative Transfusion Trigger.- Alternatives to Red Blood Cell Transfusion.-  Blood Sparing Alternatives in the Intensive Care Unit.-  Massive Transfusion in Trauma -- Transfusion in Gastrointestinal Bleeding.- Platelet Transfusion Trigger in the Intensive Care Unit.- FFP Transfusion in Intensive Care Medicine.- Transfusion-Related Acute Lung Injury -- Transfusion-Associated Circulatory Overload.