Part I: Medical Perspective.- Prenatal Screening and Diagnostic Testing -- Preimplantation Genetic Screening and Diagnostic Testing -- Medical Reasons for Pregnancy Interruption: Chromosomal and Genetic Abnormalities.- Medical Reasons for Pregnancy Interruption: Structural Abnormalities.- Medical Reasons or Pregnancy Interruption: Fetal Reduction -- Fetal Pain -- Giving Bad and Ambiguous News -- Part II: The Legal Landscape -- Legal Issues in Prenatal and Preimplantation Genetic Diagnosis -- Ethical Issues -- Religious Traditions -- Disability Perspectives -- Feminist Perspectives on Prenatal and Preimplantation Diagnosis -- PART IV: PSYCHOSOCIAL PERSPECTIVE -- Critical Aspects of Decision-Making and Grieving After Diagnosis of Fetal Anomaly.- Helping Patients Cope with Their Decisions.- A Burden of Choice-The Ripple Effect: Parents' Grief and the Role of Family and Friends.- Postscript: A Patient's Perspective.