Part I: Pre-operative haemostasis: Cell based coagulation model -- Laboratory testing of hemostasis -- Viscoelastic tests of hemostasis -- Point of care platelet function tests -- Hemostasis assessment and evaluation -- Hereditary coagulopathies -- Acquired coagulopathies -- Drug induced - Antiplatelet drugs -- Intravenous fluids and coagulation -- Split blood products -- Isolated coagulation products -- Pro-coagulant drugs -- Patient blood management. Part II: Per-operative haemostasis: In cardiac surgery -- In Hepatic Surgery -- In Pediatric Surgery -- In Obstetrics Surgery -- In Trauma -- In Neurosurgery -- In Orthopedic Surgery -- In Neuraxial and Peripheral Nerve blocks. Part III: Post-Operative: Intensive Care -- Anti-Coagulation. Part IV: Economic aspects and organization.