Introduction and Background -- History of the Face Transplantation -- Composite Tissue Allotransplantation (CTA) -- Indications of Facial Transplantation -- Evaluation of the Candidate for Facial Transplantation -- Evaluation of Donors -- Legal, Ethical and Psychological Issues in Facial Transplantation -- Face as an Organ: Functional Anatomy -- Types of Face Transplants -- Requirements for a Multidisciplinary Team -- Surgical Technique of Facial Transplantation -- Immunological Issues and Immunomodulation -- An Overview of the World`s Global Experience.