Introduction - What Is Translational Research -- Insights into heart development and regeneration -- Basis Of Cell Excitability And Cardiac Conduction System -- The Renin-Angiotensin-Aldosterone System In Cardiovascular Diseases -- Beta adrenergic receptors -- The hypothalamic-pituitary-adrenal axis in human health and disease -- Genetic Polymorphisms -- Genetic Polymorphisms and the Vascular Endothelium -- The role of microRNAs in Cardiovascular Disease -- Pathways To Myocardial Hypertrophy -- The multiple actions of the insulin-like growth factor-I signaling in the myocardium -- Calcium Cycling Circuits in Cardiac Physiology and Pathophysiology -- Inflammation and atherosclerosis -- Stress proteins and the Adaptive Response of the Heart -- The Mechanisms And Modalities Of Cell Death -- Repair of the infarcted myocardium -- Pathways to cardiac remodeling -- A Translational Approach to Probe the Arrhythmic Potential of the Heart: Therapeutic Considerations -- Animal Models Of Cardiovascular Disease -- Experimental in vitro assessment of cardiac function -- In vivo experimental assessment of cardiac function -- Non invasive imaging modalities for Cardiovascular Translational Research- Technical Considerations -- Cardiovascular Applications of Non-Invasive Imaging in Cardiovascular Diseases: from Bench to Bedside -- Molecular Imaging of Inflammation Using Echoardiography: Advances With the Use of Microbubbles -- Clinical Aspects And Genetics Of Cardiomyopathies -- Cardiorenal Syndrome: What Basic Research Can Contribute -- Clinical aspects of Cardiorenal Syndrome: consequences of therapy with the Renin-Angiotensin System Inhibitors -- Pre-, Peri-, and Post-Conditioning the ischemic myocardium: Challenges, Confounders and Expectations -- Gene Therapy for the Heart -- Cell therapy in cardiac diseases -- Moving Towards a Novel Paradigm in Drug Development for Worsening Heart Failure: The T1 Model (Mechanistic Translational Phase).