Introduction -- Nursing Informatics -- E-Health a Global Priority -- History of Computing and Technology -- The Mechanics of Computing -- Health Information Exchange: Integrating the Healthcare Enterprise -- Health Informatics Standards -- Nursing Documentation in Digital Solutions -- Independent Living Applications -- Administration Applications -- Data Privacy and Security -- The Role of the Informatics Nurse -- Research Applications -- Case Studies Introduction: Transformational Research -- Case Study 1: Nursing Informatics and eHealth in Australia -- Case Study 2: The TIGER Initiative Foundation: Technology Informatics Guiding Education Reform -- Case Study 3: Nursing Informatics - Highlights from Wales -- Case Study 4: Documenting Nursing in Health Information Systems -- The Future is a Sharp 90° Turn -- Nursing Education -- Knowledge Networks in Nursing.