PART I: OVERVIEW -- Chapter 1. Epidemiological Aspects of Hepatocellular Carcinoma -- Chapter 2. Molecular and Genetic Mechanisms of Hepatocellular Carcinoma -- Chapter 3. Role of the Immune System in Hepatocellular Carcinoma -- Chapter 4. Underlying Liver Disease -- PART II: DIAGNOSIS -- Chapter 5. Imaging of Hepatocellular Carcinoma -- Chapter 6. Pathology of Hepatocellular Carcinoma -- Chapter 7. Hepatological Evaluation and Biomarkers -- PART III: TREATMENT -- Chapter 8. Percutaneous and Laparoscopic-Assisted Ablation of Hepatocellular Carcinoma -- Chapter 9. Endovascular Treatments of Hepatocellular Carcinoma -- Chapter 10. Indications for Surgery in Cirrhotic Patients -- Chapter 11. Laparoscopic Approach for the Treatment of Hepatocellular Carcinoma -- Chapter 12. Robotic Approach for the Treatment of Hepatocellular Carcinoma -- Chapter 13. Ultrasound-Guided Liver Resection and Parenchymal-Sparing Surgery -- Chapter 14. Surgical Margins for Hepatocellular Carcinoma -- Chapter 15. Major Hepatectomies for Hepatocellular Carcinoma -- Chapter 16. R1-Vascular Surgery for Hepatocellular Carcinoma -- Chapter 17. Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) -- Chapter 18. "Re-Do" Surgery for Hepatocellular Carcinoma: Indications and Results -- Chapter 19. Liver Transplantation for Hepatocellular Carcinoma -- Chapter 20. Downstaging Strategies Prior to Liver Transplantation -- Chapter 21. Hepatocellular Carcinoma Medical Therapy -- PART IV: SPECIAL CONSIDERATIONS -- Chapter 22. Surveillance for Patients at Risk of Developing Hepatocellular Carcinoma -- Chapter 23. Hepatocellular Carcinoma Recurrence: How to Manage -- Chapter 24. Liver Biopsy: How and When -- Chapter 25. Anesthesiologic Management During Surgery for Hepatocellular Carcinoma.