Setting the Scene -- Commercial Air Transport: The History of Inflight Medical Emergencies -- Pathophysiology of Flight -- Medicolegal Issues Arising from Inflight - Medical Emergencies in Commercial Travel -- International Flight Considerations -- In-Flight Evaluation and Management of Cardiac Illness -- Respiratory Emergencies -- Neurological Illness -- Psychiatric Emergencies -- The Disruptive Passenger In-Flight -- Pediatric Considerations -- Obstetrics and Gynecology Considerations -- Infectious Disease -- Emerging Infectious Diseases -- Other Presentations -- Preflight Medical Clearance: Non-urgent Travel via Commercial Aircraft -- Pre-flight Therapies to Minimize Medical Risk Associated with Commercial Air Travel -- Ground Based Medical Support -- Use of Commercial Aircraft for Emergency Patient Transport -- Pediatric Considerations.