Diabetes Mellitus: Classification and Diagnosis -- Epidemiology and Pathogenesis of Diabetes Mellitus Type 1 -- Epidemiology and Pathogenesis of Diabetes Mellitus Type 2 -- Nontransplant Treatment Options for Diabetes Mellitus and Limitations -- History of Pancreas Transplantation -- Experimental Pancreas Transplantation -- Organ Allocation -- Donor Selection -- Pancreas Preservation -- Donor Procurement -- Surgical back-table procedures -- Recipient selection and recipient categories -- Pretransplant Evaluation and Cardiac Risk Assessment -- Recipient procedures -- Initial/Transplant hospitalization -- Imaging Studies -- Surgical Complications -- Graft Thrombosis -- Medical Complications -- Posttransplant Infections and PTLD -- Non-immunological Endocrine Graft Dysfunction -- Immunosuppressive therapy -- Donor Specific Antibodies and Antibody Mediated Rejection -- Immunobiology, Diagnosis, and Treatment of Rejection -- Pancreas Graft Pathology -- Immunology -- Endocrine Function and Metabolic Outcome (Dyslipidemia) including a comparison of Pancreas vs. Islet Transplantation -- Impact on Secondary Complications of Diabetes Mellitus -- Defining Outcomes for b-Cell Replacement Therapy -- The Current State of Pancreas Transplantation in the World - A Registry Report -- Outcome Comparison of Pancreas vs. Islet Transplantation -- Donation after Cardiac Death -- Management of Graft Failure and Retransplantation -- Transplantation of Minorities, Young and Elderly -- Long-Term Pancreas Graft Function -- Quality of Life -- Pregnancy after Pancreas Transplantation -- Formulas for successful Pancreas Transplant Programs -- Accreditation and Certification -- Economic Issues including Insurance Coverage -- The Future of Pancreas Transplantation -- Pancreas Autotransplantation -- Islet Autotransplantation -- Islet Allotransplantation -- Islet Xenotransplantation.